

Wara Samar
16th January 2025
Plexāā Partners with Panasonic Manufacturing UK for BLOOM⁴³ Medical Device Production
Plexāā, a London-based medical device startup, has joined forces with Panasonic Manufacturing UK to scale the production of its award-winning BLOOM⁴³ medical device. This innovative platform is set to transform pre-operative preparation for breast cancer surgery and reconstruction through a treatment where heat is applied to the body in what is called supraphysiological preconditioning.
The Science Behind BLOOM⁴³: Enhancing Surgical Outcomes
The BLOOM⁴³ device utilizes intermittent skin heating to release heat-shock proteins (HSPs). These proteins induce vasodilation and boost blood flow to the treated area, reducing the risk of wound healing complications such as infections and skin necrosis. Proof-of-concept clinical trials have already demonstrated the efficacy of this technology, providing hope for better surgical outcomes.

Recently recognized as the FemTech Product of the Year at MedTech Malta 2024, the BLOOM⁴³ platform is undergoing trials at Stanford University Hospital, California. The device is slated for a U.S. market launch in spring 2025, addressing a pressing need with over one million breast surgeries performed annually in the country.
Panasonic’s Role: Sustainable Manufacturing Excellence
Panasonic Manufacturing UK’s advanced facilities will serve as the contract manufacturing hub for BLOOM⁴³. The company has recently introduced a state-of-the-art RE100 application powered by its proprietary hydrogen fuel cell technology, making it Europe’s first home appliance facility to operate entirely on renewable energy. This aligns with Plexāā’s mission to deliver sustainable and impactful healthcare solutions.

Robert Blowers, Managing Director of Panasonic Manufacturing UK, remarked, “We are proud to partner with Plexāā on this exciting project. This collaboration not only highlights our ability to work across industries but also demonstrates our precision manufacturing expertise. We look forward to delivering high-quality products that will have a meaningful impact on patients.”
A Vision for Global Impact

Dr. Saahil Mehta, Founder of Plexāā, highlighted the significance of this collaboration: “Partnering with Panasonic Manufacturing UK marks a crucial milestone for us. Their renowned expertise in manufacturing excellence and commitment to green manufacturing will enable us to efficiently bring the device to market and scale up globally in line with demand.”
The collaboration is well underway, with the first manufactured products expected to roll out in early 2025. This partnership promises to significantly accelerate Plexāā’s mission of improving surgical outcomes worldwide.
About Plexāā: Pioneering Innovation in MedTech
Plexāā is dedicated to enhancing surgical outcomes through groundbreaking solutions. BLOOM⁴³, their flagship product, is the world’s first fully wearable device designed to supraphysiologically precondition the skin before breast surgery. By stimulating the release of HSPs, BLOOM⁴³ promotes improved blood flow and primes the skin for healing.

Beyond breast surgery, Plexāā is exploring applications of this technology in other surgical fields, including obstetrics for C-sections, orthopedics for joint replacements, and general and vascular surgeries. The company’s commitment to pre-operative innovation underscores its mission to improve patient outcomes across a range of medical disciplines.
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